A near-infrared fluorescent calcium probe: a new tool for intracellular multicolour Ca2+ imaging.

نویسندگان

  • Akihiro Matsui
  • Keitaro Umezawa
  • Yutaka Shindo
  • Tomohiko Fujii
  • Daniel Citterio
  • Kotaro Oka
  • Koji Suzuki
چکیده

We report a novel near-infrared fluorescent calcium probe (KFCA), which has good optical properties such as intense NIR fluorescence emission (670 nm, QY: 0.24), excellent ON/OFF ratio (120-fold), and good wavelength-compatibility with visible-light-emissive fluorophores (Fluo-4, DsRed2), and which is applicable for real-time dual-colour intracellular Ca(2+) imaging.

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عنوان ژورنال:
  • Chemical communications

دوره 47 37  شماره 

صفحات  -

تاریخ انتشار 2011